• Chondroitin / Glucosamine

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Glucosamine Sulfate

Glucosamine (Glucosamine Sulfate) is one of the top three structure components found in popular joint support products, and is the ideal supplement for joint and cartilage health.** It acts as a lubricant in order to nutritionally support healthy joints for comfortable movement.** As a key structural component in cartilage, Glucosamine Sulfate nourishes and revitalizes the cellular components within joints.** Glucosamine Sulfate, which is sourced from the shells of shrimp, lobster and crab, or from non-animal sources—also works to support mobility and flexibility by promoting range of motion.**

Chondroitin Sulfate

Chondroitin (Chondroitin Sulfate) belongs to a class of very large molecules called glucosaminoglycans, the key structural components in cartilage. Chondroitin Sulfate is manufactured from natural sources, such as shark and bovine cartilage. In humans, Chondroitin Sulfate is a major constituent of cartilage and provides structural support for cartilage and joints.**

MSM (aka Methylsulfonylmethane)

Methylsulfonylmethane, or MSM is one of the top three structural components found in popular joint support products.** It is a natural source of sulfur, a mineral that is vital in the formation of collagen, connective tissue, and healthy joint cartilage.** As an important contributor to joint and cartilage maintenance, MSM supplies vital ingredients that support the cellular components within your joints.** In addition to its beneficial effects on joints, MSM may act as an antioxidant in both fat-soluble and water-soluble compartments of the body**.

Glucosamine Sulfate Short-Term Study

A clinical study showed that subjects who took Glucosamine Sulfate after two weeks improved significantly in overall joint comfort³. Additionally, subjects taking Glucosamine Sulfate significantly scored higher in a reported comfort scale and in free range of mobility. Glucosamine was shown to effectively support overall joint health and promote comfort.

Glucosamine Sulfate Long -Term Study

A three-year study of the effects of Glucosamine Sulfate (212 subjects taking 1500 mg/day) found that Glucosamine Sulfate significantly maintained cartilage health as measured in the knee⁴. In addition, Glucosamine significantly promoted joint comfort and range of motion compared to placebo.

Chondroitin Sulfate Studies

A six-month, placebo-controlled study that evaluated the effects of 800 mg Chondroitin Sulfate on knee joint health found a statistically significant difference favoring Chondroitin Sulfate in all parameters measured, including joint comfort and walking time¹.

Another placebo-controlled study showed that subjects consuming 1 g/day Chondroitin Sulfate had significantly improved joint comfort and overall joint health (Lequesne's algofunctional index, AFI) when compared to placebo².

NOTES: Glucosamine Chondroitin MSM: Glucosamine Chondroitin MSM combos are some of the most popular supplements for joints. These three joint health ingredients (Glucosamine Chondroitin MSM), when used in the appropriate dosages, can be made part of a joint health program. Researchers continue to study Glucosamine Chondroitin MSM for joint health.

GLUCOSAMINE BENEFITS

• Ideal for joint and cartilage health**
• Glucosamine nourishes and revitalizes the cellular components within joints**
• Glucosamine acts as a lubricant in order to support healthy joints**
• Glucosamine supports mobility and flexibility by promoting range of motion**

CHONDROITIN BENEFITS

• Chondroitin provides structural support for cartilage and joints**
• Chondroitin lubricates and cushions joints**
• Chondroitin supports mobility, flexibility, and comfortable joint movement**

MSM BENEFITS

• MSM is vital in the formation of collagen, connective tissue, and healthy joint cartilage**
• MSM supports the cellular components within your joints**

References:
1. Bucsi, L. & Poor, G. Efficacy and tolerability of oral Chondroitin sulfate as a symptomatic slow-acting drug for osteoarthritis (SYSODOA) in the treatment of knee osteoarthritis. Osteoarthritis Cartilage. 1998. 6 (Suppl A); May; 31-36.
2. Mazieres B, et al. Chondroitin sulfate in osteoarthritis of the knew: a prospective, double blind placebo controlled multicenter clinical study. J Rheumatol. 2001 Jan;28(1):173-81.
3. Qui, G.X. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. Arnneimittel-Forschung. 1998. 48 (5).
4. Reginster, JY. Et al. Long-term effects of Glucosamine sulfate on progression of knee osteoarthritis. Clin J Sport Men. 2002. 12(2): 134-135.
5. Usha, P. et al. Randomised, double blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and other combination in osteoarthritis. Clinical Drug Investigations. 2004. 24 (6). 353-363.