Citalopram

Also indexed as: Celexa®

Citalopram is used to treat mental depression and is in a class of drugs known as selective serotonin reuptake inhibitor (SSRI) antidepressants.

Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)

Beneficial May be Beneficial: Side effect reduction/prevention—Taking these supplements may help reduce the likelihood and/or severity of a potential side effect caused by the medication.

Ginkgo biloba

Check Check: Other—Before taking any of these supplements or eating any of these foods with your medication, read this article in full for details.

Lithium

Depletion or interference

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

Lithium
Lithium is a mineral that may be present in some supplements and is also used in large amounts to treat mood disorders such as manic-depression. Taking lithium at the same time as citalopram can either increase the effectiveness of citalopram or increase the likelihood of developing side effects.1 Therefore, people taking citalopram together with lithium-containing supplements should contact their healthcare practitioner if they experience side effects, such as nausea, dry mouth, or sleep disturbances.

Interactions with Herbs

Ginkgo biloba
Ginkgo biloba Ginkgo biloba extract (GBE) may reduce the side effects experienced by some persons taking SSRIs such as fluoxetine or sertraline. An open-label study with elderly, depressed persons found that 200–240 mg of GBE daily was effective in alleviating sexual side effects in both men and women taking SSRIs.2 One case study reported that 180–240 mg of GBE daily reduced genital anesthesia and sexual side effects secondary to fluoxetine use in a 37-year-old woman.3

References

1. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 1073–7.

2. Cohen AJ, Bartlik B. Ginkgo biloba for antidepressant-induced sexual dysfunction. J Sex Marital Therapy 1998;24:139–45.

3. Ellison JM, DeLuca P. Fluoxetine-induced genital anesthesia relieved by Ginkgo biloba extract. J Clin Psychiatry 1998;59:199–200.