Donepezil

Also indexed as: Aricept®

Donepezil is used to treat memory loss associated with Alzheimer’s disease.

Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)

Avoid Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results.

Huperzine-A*

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

Huperzine-A
Further studies are needed to determine the long-term safety of huperizine A. Until more is known about it’s actions in the body, it is best to avoid using it together with donepezil, which also prevents the breakdown of acetylcholine.