Salmeterol is a member of the drug family known as long-acting, beta-adrenergic bronchodilators. It is inhaled by mouth, into the lungs, to treat asthma and prevent bronchospasm. Salmeterol is also used to prevent exercise-induced bronchospasm.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
 May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Coleus* |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Coleus (Coleus
forskohlii)
A test tube study demonstrated that the bronchodilating effects of salbutamol, another
beta-adrenergic bronchodilator drug, were significantly increased by the addition of
forskolin, the active component of the herb Coleus forskohlii.1 The
results of this preliminary research suggest that the combination of forskolin and
beta-agonists might provide an alternative to raising the doses of the beta-agonist drugs as
they lose effectiveness. Until more is known, coleus should not be combined with salmeterol
without the supervision of a doctor.
1. Yousif MH, Thulesius O. Forskolin reverses tachyphylaxis to the bronchodilator effects of salbutamol: an in-vitro study on isolated guinea-pig trachea. J Pharm Pharmacol 1999;51:181–6.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2005.