Pentoxifylline decreases blood thickness and improves red blood cell flexibility. Pentoxifylline is used to improve symptoms of intermittent claudication and in the treatment of other circulatory disorders.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
 May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Vitamin E |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Vitamin E
The combination of vitamin E and pentoxifylline has been used successfully to reduce damage to
normal tissues caused by radiation therapy.1
1. Delanian S, Balla-Mekias S, Lefaix JL. Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin Oncol 1999;17:3283–90.
2. Threlkeld DS, ed. Blood Modifiers, Hemorheologic Agent, Pentoxifylline. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Mar 1997, 89f–9g.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2005.