From the Manufacturer's Label:
Pycnogenol® is a unique combination of proanthocyandins obtained from the bark of the French maritime pine. As a potent natural scavenger of free radicals, Pyconogenol works to protect the body's tissues from oxidative stress and support a balanced immune system response to normal metabolic stress.
Manufactued by NOW® FoodsNot manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.