From the Manufacturer:
Ruffin' It's Natural Beefhide Chips aren't like other hide chews. They are slow roasted to lock in the beef flavor your dog loves and to preserve the high protein levels that support muscle growth. No chemical processing is used, so these premium extra thick beef hide chews remain easily digestible for your dog. They provide a good, long chew, providing important dental benefits, such as strengthening teeth and gums and helping to control tartar and plaque.