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Milk Thistle Standardized 250 mg (Silymarin)
Milk Thistle Standardized 250 mg (Silymarin)
Milk Thistle Standardized 250 mg (Silymarin)
Milk Thistle Standardized 250 mg (Silymarin)
Milk Thistle Standardized 250 mg (Silymarin)

Milk Thistle Standardized 250 mg (Silymarin)

Item #004548
Potency: 250 mg
Size: 100 Capsules

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  • Promotes healthy liver function*
  • Contains antioxidants, which help fight free radicals in the body.* Free radicals can cause oxidative stress which may damage cells.*
  • Supports overall wellness and a healthy lifestyle*
  • Contains a one-month supply of easy-to-swallow capsules; capsules can also be opened and prepared as a tea


Modern research supports the continued use of this traditional herb to promote healthy liver function.*

Milk thistle or Silybum marianum is an annual belonging to the daisy family. It is named for its green, spiny leaves that release a milky sap when broken. But the health-promoting benefits come from its seed-like fruits. Merely millimeters in size, these tiny fruits contain silymarin, a complex mixture of plant-based nutrients called flavonoids.1

For thousands of years, milk thistle has been used as a health tonic most prized for supporting liver health.* Originally native to areas of Europe, Russia, Asia and Africa, milk thistle was later naturalized in North and South America and has been used throughout the world. In Ancient Greece it was used as a tonic to promote liver health.*1

Traditional systems of Chinese and Indian medicine also used milk thistle to revitalize the liver and gallbladder.*1 Throughout the Middle Ages, it was believed to detoxify the liver.*2 Despite its frequent and common use, the active components in milk thistle were not identified until 1968.1

milk thistle in bowl

Spotlight on Liver Health

The liver is the largest single internal organ weighing around 3 lbs.3,4 After digestion, nutrient-rich blood is delivered directly to the liver where it is filtered before being distributed to the rest of the body. The liver detoxifies blood, metabolizes nutrients and plays many more critical roles that impact nearly every aspect of health.

Milk thistle contains special flavonoids that help maintain healthy liver function.* Flavonoids are plant-based compounds that can be beneficial for human health.* There are thousands of different flavonoids in the plant kingdom. The complex group of flavonoids found in milk thistle is collectively known as silymarin. Silymarin supports the outer cell membrane of liver cells.* Cell membranes control what is allowed to enter a cell, helping to protect the cell from outside threats such as toxins.

Silymarin also contains important antioxidant properties to help fight free radicals in the body.* Free radicals can contribute to oxidative stress, which in turn may contribute to the premature aging of cells. Free radicals occur naturally in the body but can be compounded by external factors like pollution and smoking. The beneficial flavonoids and antioxidants in milk thistle also stimulate the production of important proteins needed for the formation of new liver cells.*

Main Function of the Liver

icon digestion

Produces bile, important for the digestion and absorption of fats5

icon nutrition
Nutrient Storage

Stores vitamins A, D, & E, iron and copper5

icon detoxification

Breaks down certain drugs and removes alcohol from the blood5

icon blood clotting
Blood Clotting

Synthesizes proteins needed for proper blood clotting5

Milk Thistle
Is Silymarin the only beneficial component of milk thistle?

It is true that silymarin has been identified as the active component in milk thistle responsible for promoting liver health.* Silymarin also has important antioxidant properties.* Yet silymarin only makes up about 1.5-3% of the dry weight of the small, seed-like milk thistle fruits.1 The rest of these fruits are composed of proteins, fatty acids, sugars, and other phytonutrients with beneficial properties. Puritan’s Pride offers both standardized and non-standardized milk thistle extracts. A standardized milk thistle extract will provide a set amount of silymarin whereas an unstandardized extract will provide the goodness of the whole herb.

When should I take milk thistle?

Your daily intake of milk thistle supplements can be consumed with one meal or can be taken at separate meals throughout the day.

Can you make milk thistle tea?

Milk thistle seeds have long been roasted and used as a coffee substitute. Puritan’s Pride® milk thistle capsules may be opened and prepared as a tea. If you choose to consume your milk thistle supplements in this manner, we recommend enjoying your milk thistle tea along with a meal. The active constituent in milk thistle, silymarin is best absorbed when taken with food.


  • 1.Bijak M. Molecules. 2017 Nov 10;22(11):1942.
  • 2.PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Bethesda, MD: NCI; 2019. Accessed September 29, 2020.
  • 3. Gropper SS, Smith JL, Groff, JL. Fifth edition. Belmont, CA: Wadsworth/Cengage Learning; 2009.
  • 4. Johns Hopkins Medicine. Johns Hopkins Medicine Health website. Accessed September 25, 2020.
  • 5. Kalra A, et al. Physiology, Liver. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan.

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