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Liquid Vitamin D3 5000 IU
Liquid Vitamin D3 5000 IU
Liquid Vitamin D3 5000 IU
Liquid Vitamin D3 5000 IU

Liquid Vitamin D3 5000 IU

Item #030405
Potency

5000 IU

Size

2 oz Liquid

Earn up to 110 Puritan's Perks points. Learn More


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immune icon

Not sure where to start
with immune health?

Then this is a great place to begin.
This content is intended as general information. We encourage you to explore the full Puritan’s Pride’s® Immune Health offerings for product-specific benefits.

Vitamin D for Immune Health

Vitamin D is a fat-soluble vitamin that can be obtained through the diet or synthesized in the skin upon exposure to sunlight. Vitamin D3, the form of vitamin D formed in the skin, is a potent and active form of the vitamin. Vitamin D2 is a vitamin D analog formed in plants, mushrooms and yeasts during photosynthesis. While vitamin D2 is sometimes used in food fortification, Puritan’s Pride supplements provide the active form.

Vitamin D plays a regulatory role in the growth, differentiation, and proliferation of different types of white blood cells.8** It is important to regulate these processes to maintain immune balance. Think of a thermostat set to 70 degrees.

When the temperature falls below 70 degrees the heat comes on but once the temperature is reached, the heat needs to turn off or else the temperature will continue to rise indefinitely. The same delicate balance is needed for our immune systems to maintain optimal health.

The T and B cells of the adaptive immune system are both regulated by vitamin D.** Many cells of the innate immune response also require vitamin D such as monocytes which need it to mature properly.** Adequate concentrations of vitamin D are also necessary for the synthesis of important proteins with immune-fighting properties.8**

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Why Supplement with Vitamin D?

As many as 96% of Americas do not get enough vitamin D from food alone.9

Did you know, Vitamin D is considered a nutrient of public health concern? This is because many Americas are not getting enough vitamin D in their diets and low intakes are associated with health concerns.

This is partly because natural food sources of vitamin D are limited and not always appealing. They include cod liver oil, liver and some types of fatty fish such as mackerel, salmon, and sardines. In the US, milk but not all dairy products, is fortified with vitamin D. It is important to check the label on products like cheese and yogurt to see if they were made with fortified milk.

The RDA for vitamin D is currently 15-20 mcg/day depending on age.

However, this level was established based on the amount of vitamin D needed to maintain bone health.** Many health experts argue that higher intakes of vitamin D are necessary for overall optimal health. A daily intake of 50 mcg (2,000 IU) is frequently recommended for most healthy adults.12


Unlike most vitamins that can only be obtained from the diet, our bodies produce vitamin D when the skin is exposed to sunlight. When evaluating if sun exposure is enough to meet your daily vitamin D needs, consider the following factors.

AGE

As we age, the skin produces vitamin D less efficiently. Vitamin D absorption may also decrease with age, making vitamin D supplementation especially beneficial for older individuals.

SUNSCREEN

When used as directed, a sunscreen graded SPF-10 will block 90% of UVB radiation reaching the skin.10 UVB radiation is needed to stimulate production of vitamin D.

LOCATION

Residents of northern climates may have inadequate exposure to sunlight in order to produce sufficient vitamin D, especially during the winter months.

CLOTHING

Wearing protective clothing such as hats and long sleeves inhibits the body’s natural production
of vitamin D.

SUN INTENSITY

The stimulation of vitamin D production in skin can depend on the intensity of the sun’s UVB rays. When you are shorter than your shadow, UVB radiation is often not strong enough to produce vitamin D.11 Air pollution and the presence of clouds can also have a major impact on the intensity of UVB radiation that reaches the ground.

  • References
  • 8. Gropper SS, Smith JL, Groff, JL. Fifth edition. Belmont, CA: Wadsworth/Cengage Learning; 2009.
  • 9. Dickinson A, MacKay D. Nutr J. 2014;13:14.
  • 10. Council on Environmental Health, Section on Dermatology, Balk SJ. Pediatrics. 2011 Mar;127(3):588-97.
  • 11. Gorham E. Vitamin D wiki website. October 2015. Accessed July 2, 2020. https://vitamindwiki.com/The+Shadow+Rule+%E2%80%93+you+make+Vitamin+D+when+you+are+taller+than+your+shadow+%E2%80%93+1992
  • 12. Calder PC, et al. Nutrients. 2020;12(4):1181.

What is the Immune System?

Every day, your body is bombarded by foreign substances from the outside world. Credit card pin pads, bathroom faucets, cell phones, literally everything you touch is covered in tiny microorganisms. Not all microorganisms are bad, in fact there are trillions of bacteria found in and on the human body which cause no harm, or in some cases are even beneficial to human health.

However, there are also less favorable microorganisms found in the environment. The main function of your immune system is to protect you from external threats and keep you healthy.

Think of your immune system as your body’s security team, trained to recognize and remove any threats while protecting your body’s peaceful residents.

The first line of defense is to restrict the entry of unwanted foreign materials. The skin creates an excellent physical barrier but unwanted guests may still be inhaled or ingested. The acidity of stomach acid, mucosal membranes, and the presence of antibodies in saliva and tears all further help to prevent the entry of these substances into the body.

Four Main Functions
of the Immune System

icon exclusion
Exclusion Barrier

Physical barriers keep pathogens from entering the body – e.g. skin, mucosa layer of GI tract, antibodies in saliva, pH of stomach

icon recognition
Recognition

If substances get through the exclusion barrier, they need to be recognized as non-self

icon elimination
Elimination

Elimination only of unwanted threats, not self or friendly bacteria

icon memory
Memory

Immune memories allow for fast recognition and elimination of repeat offenders


1

Your First Line of Defense: Innate Immune System

If a non-beneficial microorganism is able to pass through your body’s first line of defense, it must be recognized by your immune system. Recognition is an important feature of your patrolling security team. Without it, your immune system would attack non-threatening foreign substances and even your own cells. Undesirable substances are recognized by white blood cells that send messages akin to sounding an alarm, drawing more white blood cells to the area. There are many different types of white blood cells, also called leukocytes, that all work together to orchestrate the appropriate immune response. The elements of the immune system discussed thus far are all considered part of the innate response.

Characterized as being fast and non-specific, the innate immune system responds within minutes or hours.1 Once the innate immune system has identified a threat, it seeks to eliminate it. The various white blood cells of the innate immune system each fight these threats in their own unique ways. Some will trigger an inflammatory response while others will deal with it directly by engulfing it or releasing toxic chemicals. Since the innate immune response is non-specific, the response is generally the same regardless of whether the same pathogen is encountered numerous times.


2

Your Second Line of Defense: Adaptive Immune Response

If a non-beneficial microorganism is able to pass through your body’s first line of defense, it must be recognized by your immune system. Recognition is an important feature of your patrolling security team. Without it, your immune system would attack non-threatening foreign substances and even your own cells. Undesirable substances are recognized by white blood cells that send messages akin to sounding an alarm, drawing more white blood cells to the area. There are many different types of white blood cells, also called leukocytes, that all work together to orchestrate the appropriate immune response. The elements of the immune system discussed thus far are all considered part of the innate response.

Characterized as being fast and non-specific, the innate immune system responds within minutes or hours.1 Once the innate immune system has identified a threat, it seeks to eliminate it. The various white blood cells of the innate immune system each fight these threats in their own unique ways. Some will trigger an inflammatory response while others will deal with it directly by engulfing it or releasing toxic chemicals. Since the innate immune response is non-specific, the response is generally the same regardless of whether the same pathogen is encountered numerous times.

Factors that
Affect Immune Health

Your immune system is always patrolling your body to keep you at your best, but you need to keep your immune system healthy too. Every day you need to provide your immune system with the energy and nutrients it needs to function optimally.

age block

AGE: The immune response starts to weaken around age 60 and continues to weaken with age.2

sleep block

SLEEP: Important immune proteins called cytokines are released while we sleep. Sleep deprivation leads to decreased immune function as well as increased recovery times.3

stress block

STRESS: Both physical and emotional stress can negatively impact the immune system. The stress hormone cortisol has been shown to decrease white blood cell numbers.7

smoking block

SMOKING:: Smoking causes dysfunction of white blood cells involved in both innate and adaptive immunity.5 It is estimated that 1.1 billion people in the world are smokers.6

sleep block

PHYSCIAL ACTIVITY: Regular moderate-intensity exercise achieved on a near-daily basis is associated with better immune health with age. More than 80% of U.S. adults are not meeting guidelines for both aerobic and muscle-strengthening activities.4

stress block

NUTRITION: The immune system needs proper nutrients to function optimally. There are a number of vitamins, minerals and other nutrients that are widely recognized for their role in supporting immune health.**

Immune
Myths & FAQs
Myth: All immune support supplements work the same way.

Because the immune system is such a complex system, there is not a one-size-fits-all approach to supporting immune health. The various different types of white blood cells, immune proteins, and tissues and organs all have different nutrient requirements. Taking a single nutrient for immune health may assist in supporting one of these aspects of immune health, but if you are lacking other nutrients in your diet, then you may be falling short in getting total immune support.**

Myth: The immune system is stronger in the summer.

The immune system works year-round to keep you healthy no matter what the season. Depending on location and lifestyle factors, vitamin D status may be higher in the summer to better support certain aspects of immune health.** Winter weather conditions such as dry air may also affect immune health. It is still important to support your immune health every day throughout the year for optimal functioning.

FAQ: How can you boost your immune system?

The immune system should not be “boosted” beyond normal, optimal functioning. In fact, many autoimmune diseases are characterized by an overactive immune system that starts attacking its own cells. There are however lifestyle changes that you can make to help support normal functioning of the immune system. These include getting adequate sleep, engaging in regular physical activity, managing stress, eating a balanced diet and getting adequate amounts of immune supporting nutrients.

FAQ: Where is the immune system?

The immune system is a complex network of organs, cells, tissues and proteins found throughout the body. It includes the thymus, spleen, bone marrow, skin, tonsils and Peyer’s patches in the intestines. The lymph system allows white blood cells of the immune system to patrol the entire body looking for foreign invaders.

References:

  • 1. Gombart AF, Pierre A, Maggini S. Nutrients. 2020;12(1):236.
  • 2. Pawelec G, Larbi A, Derhovanessian E. J Comp Pathol. 2010;142 Suppl 1:S39-S44.
  • 3. Krueger JM, Majde JA, Rector DM. Cytokines in Immune Function and Sleep Regulation.; 2011. doi:10.1016/B978-0-444-52006-7.00015-0
  • 4. President’s Council on Sports, Fitness & Nutrition. U.S. Department of Health and Human Services Website. Updated January 26, 2017. Accessed July 2, 2020. https://www.hhs.gov/fitness/resource-center/facts-and-statistics/index.html
  • 5. Qiu F, Liang CL, Liu H, et al. Oncotarget. 2017;8(1):268-284.
  • 6. Tobacco. https://www.who.int/news-room/fact-sheets/detail/tobacco. Accessed March 24, 2020.
  • 7. McGregor BA, Murphy KM, Albano DL, Ceballos RM. Stress. 2016;19(2):185-191.

Why Choose Puritan’s Pride?

Getting the most out of life every day is what inspires us to deliver over 3,000 outstanding products that help you achieve your health and wellness goals.

We take pride in manufacturing the vitamins, minerals and herbal supplements that complement your healthy lifestyle, plus we offer essential oils, nutritious foods and more.

So get out there and embrace life… because the journey is your reward.

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for Over 45 Years


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Customer Reviews
Rated 5 out of 5 by from liquid vitamin d works for me! Vitamin D supplementation was recommended by my PCP. I prefer the liquid formulas. Puritan's Pride is excellent quality overall, and a very fair price.
Date published: 2019-11-16
Rated 5 out of 5 by from Great product I bought this a month ago and it works very well. I am better able to tolerate the sunflower seed base.
Date published: 2019-11-06
Rated 1 out of 5 by from Vitamin D Contaons Sunflower oil as 1st ingredient not vitamin D
Date published: 2019-10-15
Rated 5 out of 5 by from Great Product I’ve been using this for around 6 months my Vitamin D level has increased & I am very pleased with Puritans Pride Vitamin D liquid. I will continue to use this & my doctor is happy also.
Date published: 2019-10-07
Rated 5 out of 5 by from It works! Great products. My levels were low and now they are up. I stopped for a week to try another product and I crashed.
Date published: 2018-03-16
Rated 4 out of 5 by from Honest Review I really like this product and do believe it is supplying its claimed amount of Vitamin D. I had to pull a full star from my rating because the bottle it comes in sucks. The dropper dispenser is made a little too long for the bottle and it leaks and just doesn't cut it. I like the product so much I deal with it.
Date published: 2017-11-19
Rated 5 out of 5 by from Vitamin D I love this product it has helped me reach my goal
Date published: 2017-03-26
Rated 4 out of 5 by from Good Product First time using liquid vitamin D but am satisfied with the results and will continue to use Puritan's Pride.
Date published: 2017-03-16
Rated 5 out of 5 by from Great product. recommended. This product tastes great and does not contain artificial stuff, just sunflower oil and natural orange flavor. So you are getting your vitamin D without all the unnecessary additives found in other products. Plus it tastes good so you can put it directly on your tongue. I will definitely recommend this product.
Date published: 2017-02-20
Rated 5 out of 5 by from Seems real good I bought this as my elderly Mom can no longer take pills. i also bought it for myself. this product seems to be good. it's easy to take and the taste is good. i'll see if it's working after my next blood test.
Date published: 2017-01-01
Rated 5 out of 5 by from EXCELLENT My Vitamin levels were low, now they are up to where it should and i am feeling great
Date published: 2016-12-28
Rated 5 out of 5 by from Great tasting Good value. Good taste. Dropper a little flimsy. Other than that. Awesome. Will reorder.
Date published: 2016-12-16
Rated 5 out of 5 by from Excellent! Really good! And good taste. Will order it again.
Date published: 2016-03-01
Rated 5 out of 5 by from great product, great price Have no complaints and will continue to use especially during long overcast winter days when I can't get my D from the sun.
Date published: 2016-01-14
Rated 5 out of 5 by from Awesome Vitamin It works fast. It tastes good and is easily absorbed into my system. I highly recommend it.
Date published: 2016-01-10
Rated 5 out of 5 by from Easy to use and trustworthy Can't be beat anywhere for freshness and value and ease of use . This product is great
Date published: 2016-01-04
Rated 5 out of 5 by from Fair When I purchased this I believed it to be. Sublingual. This is way too thick to do sublingual so from that stand point I am disappointed and would not purchase again. I know from my history with puritans pride products they are a good company with good products.
Date published: 2016-01-03
Rated 5 out of 5 by from Great vit D product Great tasting, quality product. My kids look forward to taking it each morning.
Date published: 2015-11-29
Rated 5 out of 5 by from Really Like It... Very satisfied with this product, the price is right, good tasting will buy from here all the time now....
Date published: 2015-08-29
Rated 5 out of 5 by from Oh No - Not on Back Order????!! Cannot live without. This is the greatest, especially for someone like me who has health issues. Just opened my last bottle and check daily to see if in yet. That ought to tell you how much this product does for me and I live in FL. My daughter lives in northern Ohio and uses this every day to supplement the lack of sunshine.
Date published: 2015-05-14
Rated 5 out of 5 by from A full thumbs-up. This is precisely what I have been seeking. The ingredients closely match my a'NO-GRAIN' dietary profile, and the dropper has two levels depending on choice. I am so satisfied that I gave a friend one of the bottles I ordered.
Date published: 2015-05-03
Rated 5 out of 5 by from Liquid D I have found that anytime I can get a liquid vitamin supplement, it seems to stay in my system. This is a good product for Winter time since my getting outside is minimal.
Date published: 2015-04-21
Rated 4 out of 5 by from Liquid D3 Pro:I take my 10,000 iu under my tongue. because of the oil base absorption is a little less than fast. Natural energy came up within 6 hours. Con: Dosage per bottle is low. One bottle lasted about 10 days.
Date published: 2015-04-13
Rated 5 out of 5 by from Excellent Product I ordered this supplement because my Vitamin D results is very low. I live the taste of this product andI feel marvelous sinceI started taking it. Will buy it again....Love everything I have purchased especially this product.
Date published: 2015-04-02
Rated 4 out of 5 by from Quick and easy No bad taste, quick to take and will work well for me!
Date published: 2015-03-20
Rated 5 out of 5 by from Start the day with D3 I like the drops. I take so many pills/vitamins all day that I find it very fast/easy to just drop a dropper full down the hatch w/my first meal of the day and am currently looking to buy all liquid supplements.
Date published: 2015-02-26
Rated 5 out of 5 by from Must have product I consider D3 to be the most important product I take. Friends think I am selling it because I have so much good to say about it. VERY effective product and I would not be without it.
Date published: 2015-02-25
Rated 5 out of 5 by from Vitamin D drops Love the taste. Very easy to take. This is the best Vit D drops I have found. Very satisfied.
Date published: 2015-01-05
Rated 4 out of 5 by from Very satisfied First time to take vit D. Much more pleasant than pills! Easy to take, taste very pleasant--- does not leave after-taste.
Date published: 2014-11-20
Rated 5 out of 5 by from excellent liquid vitamin D3 5000 iu the liquid vitamin D absorbs much better than capsules or pills. our test results are the proof.
Date published: 2014-10-24
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