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Ubiquinol 300 mg
Ubiquinol 300 mg
Ubiquinol 300 mg
Ubiquinol 300 mg
Ubiquinol 300 mg

Ubiquinol 300 mg

Item #051594
Potency: 300 mg
Size: 30 Rapid Release Softgels

Earn up to 1280 Puritan's Perks points.

  • An advanced, active form of Co Q-10 that is body ready for antioxidant health*
  • Supports a healthy heart and cardiovascular system*
  • Supports cellular energy production within your heart and muscles*
  • Supports good oral health, which has been linked to cardiovascular health*
  • Contains a 20-day supply of easy-to-swallow, rapid-release softgels that offer superior absorption


Puritan’s Pride® Ubiquinol 300 mg

Puritan’s Pride® Ubiquinol 300 mg is our highest-potency ubiquinol product providing 300 mg of ubiquinol in just one daily softgel. This formula is ideal for those looking for a high-dose ubiquinol, but don’t want to deal with swallowing lots of pills.

High daily doses of ubiquinol can help to increase the levels of Co Q-10 in the body.* A study in human volunteers demonstrated a daily dose of 300 mg of Ubiquinol increase levels of Co Q-10 in the blood 9x’s above their starting levels in two weeks.1 That is 150% more than the rise in blood levels of Co Q-10 seen in subjects receiving 90 mg of Ubiquinol for the same period of time.1 Raising blood levels of Co Q-10 may be particularly important for older individuals or those on Statin medications.

Researchers from Columbia University found Statin medications can deplete blood levels of Co Q-10 as much as 51% after 30 days of use.3 Ubiquinol can replenish what statin medications may deplete but it is not intended to serve as a replacement for Statin therapy. Do not discontinue taking any prescribed medications while supplementing with Ubiquinol.

One Serving Per Day

Icon Promotes Heart Health*

Clinically studied to
promote heart health*

Icon Beneficial Healthy Aging*

healthy aging*

Icon Helps support
healthy blood pressure*†

Helps support
healthy blood pressure*†

Promotes oral
and gum health*

Promotes oral
and gum health*

Ubiquinol: The Advanced Co Q-10

You are probably familiar with coenzyme Q-10 (Co Q-10). But did you know that it exists in two forms?

Originally, Co Q-10 supplements were only available as Co Q-10 in its oxidized form, ubiquinone. Now the reduced form of Co Q-10, ubiquinol is also readily available in dietary supplements. Co Q-10 is recycled back and forth between these two forms depending on the demands of the body.

Ubiquinol is the most common form of Co Q-10 found in the body. In fact, it accounts for about 80% of the total Co Q-10 found in the plasma, intestines and liver.1 Ubiquinol is the active form that is ready to fight free radicals.* Free radicals are unstable compounds that can lead to oxidative stress which can cause damage to cells. When ubiquinol encounters a free radical, it neutralizes the free radical in a process that converts ubiquinol to ubiquinone.* To fight another free radical, ubiquinone must first be converted back to ubiquinol.*

Supplementing with either ubiquinol or ubiquinone is effective at restoring low blood levels of Co Q-10 to the population average.2 However, ubiquinol may be a better choice for older adults, those with high Co Q-10 needs, or anyone wanting to quickly replenish their Co Q-10 levels.* Ubiquinol supplements have been shown to increase levels of Co Q-10 in the blood by 110% more when compared to regular Co Q-10 supplements.*


Ubiquinol levels in the body reach their peak by age 20 and
decrease by up to 50% in different parts of the body by age 80.3


Ubiquinol Levels

Statins can lead to a 51%
decrease in Ubiquinol plasma levels
within 30 days of use.++


Dietary Intake

The average dietary intake of Ubiquinol is only about 3-5 milligrams per day.3 Not nearly enough to replenish levels lost due to age-related decline or prescription drugs.


How much do I need?

Depending on your needs, Ubiquinol supplementation recommendations can range anywhere from 60-600 milligrams per day to increase tissue concentrations.

++ Ubiquinol is not intended to serve as a replacement for statin therapy, nor should you discontinue taking any prescribed medications while supplementing with Ubiquinol
Ubiquinol’s Role in Supporting Energy*

Ubiquinol acts as a key component in our mitochondrial machinery involved in making up a large percentage of the body’s energy.

This energy is produced via the electron transport chain in the form of ATP (adenosine triphosphate) across the inner mitochondrial membrane.1

Ubiquinol for
Heart Health*

Ubiquinol is vital for the muscle of the heart.2

The reason is due to the heart’s requirement of a constant supply of ATP energy. While blood vessels transport blood, the heart provides the force to pump blood around the body.

As a result, Ubiquinol concentration is an important determination of heart function and cardiovascular health.5 Historically, scientific studies evaluating the effects of Ubiquinol have been mainly focused on its potential support to cardiovascular health.9*

Statins and Ubiquinol

Ubiquinol supplements can help replenish what is lost with age or what statin medications deplete.

However, Ubiquinol is not intended to serve as a replacement for statin therapy, nor should you discontinue taking any prescribed medications while supplementing with Ubiquinol.

Ubiquinol supplementation recommendations can range
anywhere from 60-600 milligrams per day.

As you get older opt for a higher dose Ubiquinol supplement, but don’t forget to choose a highly purified Ubiquinol like Q-Sorb™ Ubiquinol.

chart Ubiquinol food amount

Ubiquinol FAQs

Why should I supplement with Ubiquinol?

As we get older, our natural Ubiquinol levels decline, especially in the heart, other organs and tissues with high-energy requirements, and in outer layers of the skin. A highly purified Ubiquinol supplement like Q-Sorb™ may assist in keeping these levels up, especially as we get older.*

Can I get Ubiquinol from my diet?

Although Ubiquinol can be found in foods like fish, pork, and beef, we may not obtain enough Ubiquinol in our daily diets, especially as cooking methods like frying reduces the natural Ubiquinol content in these foods. Following a plant-based diet may also mean lower Ubiquinol intake. By taking a Ubiquinol supplement, this gap in our diet may be filled.

How does Ubiquinol work?

Ubiquinol is needed for the production of ATP (adenosine triphosphate). ATP is the energy our body cells use to perform their daily activities optimally. Certain cells in the body are more metabolically active and have higher energy requirements. Ubiquinol levels are naturally higher in the heart and skeletal muscles for this reason.

I take a statin and my doctor recommended I take Ubiquinol, why?

Studies have found that statins deplete Ubiquinol levels in the body. A Ubiquinol supplement can help replenish what a statin medication might deplete. Please be aware that Ubiquinol is not intended as a replacement for statin therapy, nor should you discontinue any prescription medication while supplementing with Ubiquinol.

What is Q-Sorb™ Ubiquinol?

Puritan's Pride's own Q-Sorb™ Ubiquinol is a naturally fermented, highly purified form of Ubiquinol. We take the same form of Ubiquinol your body naturally produces and enrobe it in naturally sourced oils to improve absorption. Q-Sorb™ is available in rapid-release softgels in various dosages to suit your needs.

Is Ubiquinol an energy stimulant or will give you the "jitters"?

Although Ubiquinol helps the body produce energy, this energy production is at a cellular level so Ubiquinol will not give you the sudden energy boost you may get from consuming caffeine or a sugary snack.

If I take a multivitamin and mineral every day, do I need Ubiquinol?

Most multivitamin and mineral supplements contain no or very low quantities of Ubiquinol. Additionally to support absorption, Ubiquinol is best taken in a softgel along with a meal. Ubiquinol supplementation may be especially important as we age as our Ubiquinol levels naturally decline as we get older.

Is Ubiquinol easily absorbed in tablets or in powder form?

Efficient absorption of any ingredient is dependent on a variety of factors, but with Ubiquinol, delivery form is of particular importance. Taking Ubiquinol in a softgel rather than in a powder form makes Ubiquinol more absorbable. By choosing a high purity Ubiquinol like Q-Sorb™ Ubiquinol, you know you’re getting not only quality you can trust, but also that your body is going to absorb it more efficiently too.

Can I stop my cholesterol-lowering medication if I use Ubiquinol?

No. Ubiquinol is not intended to serve as a replacement for statin medication, nor should you discontinue taking any prescribed medications while supplementing with Ubiquinol without consulting your doctor.

  • 1. Nohl H, Gille L, Staniek K. The biochemical, pathophysiological, and medical aspects of ubiquinone function. In: Annals of the New York Academy of Sciences. ; 1998. doi:10.1111/j.1749-6632.1998.tb09919.x
  • 2. Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: Recent developments. In: Molecular Biotechnology. ; 2007. doi:10.1007/s12033-007-0052-y
  • 3. Littarru GP, Lambrechts P. Coenzyme Q 10: Multiple benefits in one ingredient. OCL - Ol Corps Gras Lipides. 2011;18(2):76-82. doi:10.1684/ocl.2011.0374
  • 4. Langsjoen PH, Langsjoen AM. Overview of the use of CoQ10 in cardiovascular disease. BioFactors. 1999. doi:10.1002/biof.5520090224
  • 5. Langsjoen H, Langsjoen P, Langsjoen P, Willis R, Folkers K. Usefulness of Coenzyme Q10 in clinical cardiology: A long-term study. Mol Aspects Med. 1994. doi:10.1016/0098-2997(94)90026-4
  • 6. T. R, A. N, R. S, K. C, S. D. Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol. 2004;61(6):889-892. doi:10.1001/archneur.61.6.889
  • 7. Mizuno K, Tanaka M, Nozaki S, et al. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition. 2008. doi:10.1016/j.nut.2007.12.007
  • 8. Cooke M, Iosia M, Buford T, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008. doi:10.1186/1550-2783-5-8
  • 9. Littarru GP, Tiano L. Clinical aspects of coenzyme Q10: An update. Nutrition. 2010. doi:10.1016/j.nut.2009.08.008
  • 10. Ernster L, Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. BBA - Mol Basis Dis. 1995. doi:10.1016/0925-4439(95)00028-3
  • †Helps support healthy blood pressure levels already in a normal range

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